Circadian Rhythm Biology

This is my most personal work. I became pre-diabetic, and despite having studied diabetes for many years, I didn’t know what specifically to do to reverse this. That’s when I remembered Satchin Panda’s work at Salk Institute. His lab showed that limiting food intake to a limited number of hours a day (vs around the clock) had huge metabolic benefits. I tried this approach – time-restricted eating – which helped me change my eating habits and quickly reverse the pre-diabetes.

In another success story, my dad had been struggling with his type 2 diabetes. He was loosely following time-restricted eating, but he wasn’t benefitting as much as I thought he could be, and I wondered why. I had the idea that his long-acting insulin, which meant high levels of insulin around the clock, was tricking his body into thinking it was fed all the time, and making his insulin resistance worse. His doctor told him to take more long-acting insulin, but this hadn’t helped. My dad and I decided to reduce his long-acting insulin, and he immediately lost weight, had better eating habits, and brought his HbA1c down to almost non-diabetic levels.

Read about these two stories here: