A database for every disease

This is one of the projects that I’m most passionate about. As we look to solve the world’s diseases, we don’t have a good way to collate information from the primary research literature. Having this information organized in a standardized way could help us quickly make sense of research that’s been done and what research should be done for each disease. This post puts forward a framework to organize information for diseases.

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A case for precise insulin dosing in type 2 diabetes

A case for precise insulin dosing in type 2 diabetes

This post was originally published at blog.mycircadianclock.org

This is the story of how I helped my dad with his diabetes. After reversing my own pre-diabetes and drawing on research from circadian rhythm biology, I made a recommendation to my dad that went against his doctor’s advice — to reduce his dose of long-acting insulin and make up for it with short-acting insulin. This turned out to be the linchpin that helped him achieve lower blood sugar levels.

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Achieving normal blood sugar levels in type 1 diabetes

Achieving normal blood sugar levels in type 1 diabetes

A recent study described a group of type 1 diabetic (T1D) patients that have achieved normal blood sugar levels by using a low carbohydrate diet [1]. No therapeutic interventions to date, with the exception of islet transplants, have achieved normal blood sugar levels on a cohort-wide basis. Here, I summarize the data from this low carbohydrate study, highlight the significance of the results, and include a note of caution around implementing this type of diet.

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